Fix SMS_PORTALWEB_CONTROL_MANAGER (Internal Server Error) in SCCM 2012

Good day
For some reason SCCM 2012 ( System Center Configuration Manager 2012) may report the following error:

Portal Web Site Control Manager detected PORTALWEB is not responding to HTTP requests.  The http status code and text is 500, Internal Server Error.

Possible cause: Internet Information Services (IIS) isn't configured to listen on the ports over which PORTALWEB is configured to communicate. 
Solution: Verify that the designated Web Site is configured to use the same ports which PORTALWEB is configured to use.

Possible cause: The designated Web Site is disabled in IIS. 
Solution: Verify that the designated Web Site is enabled, and functioning properly.

For more information, refer to Microsoft Knowledge Base.

The Fix is easy by using the following command:

aspnet_regiis.exe /iru

The Aspnet_regiis.exe file can be found in one of the following locations:

%windir%\Microsoft.NET\Framework\v4.0.30319

%windir%\Microsoft.NET\Framework64\v4.0.30319 (on a 64-bit computer)

Hope That Help